Identification and Characterization of Novel Small-Molecule SMOX Inhibitors

The major intracellular polyamines spermine and spermidine are abundant and ubiquitous compounds that are essential for cellular growth and development. Spermine catabolism is mediated by spermine oxidase (SMOX), a highly inducible flavin-dependent amine oxidase that is upregulated during excitotoxi...

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Detalles Bibliográficos
Autores principales: Furbish, Amelia B., Alford, Ahmed S., Burger, Pieter, Peterson, Yuri K., Murray-Stewart, Tracy, Casero, Robert A., Woster, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504029/
https://www.ncbi.nlm.nih.gov/pubmed/36135832
http://dx.doi.org/10.3390/medsci10030047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504029/
https://www.ncbi.nlm.nih.gov/pubmed/36135832
http://dx.doi.org/10.3390/medsci10030047

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