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Identification and Characterization of Novel Small-Molecule SMOX Inhibitors
The major intracellular polyamines spermine and spermidine are abundant and ubiquitous compounds that are essential for cellular growth and development. Spermine catabolism is mediated by spermine oxidase (SMOX), a highly inducible flavin-dependent amine oxidase that is upregulated during excitotoxi...
Autores principales: | Furbish, Amelia B., Alford, Ahmed S., Burger, Pieter, Peterson, Yuri K., Murray-Stewart, Tracy, Casero, Robert A., Woster, Patrick M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504029/ https://www.ncbi.nlm.nih.gov/pubmed/36135832 http://dx.doi.org/10.3390/medsci10030047 |
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