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Evolutionary Invariant of the Structure of DNA Double Helix in RNAP II Core Promoters

Eukaryotic and archaeal RNA polymerase II (POL II) machinery is highly conserved, regardless of the extreme changes in promoter sequences in different organisms. The goal of our work is to find the cause of this conservatism. The representative sets of aligned promoter sequences of fifteen organisms...

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Detalles Bibliográficos
Autores principales: Melikhova, Anastasia V., Anashkina, Anastasia A., Il’icheva, Irina A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504043/
https://www.ncbi.nlm.nih.gov/pubmed/36142782
http://dx.doi.org/10.3390/ijms231810873