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Facile Access to 2-Selenoxo-1,2,3,4-tetrahydro-4-quinazolinone Scaffolds and Corresponding Diselenides via Cyclization between Methyl Anthranilate and Isoselenocyanates: Synthesis and Structural Features

A practical method for the synthesis of 2-selenoxo-1,2,3,4-tetrahydro-4-quinazolinone was reported. The latter compounds were found to undergo facile oxidation with H(2)O(2) into corresponding diselenides. Novel organoselenium derivatives were characterized by the (1)H, (77)Se, and (13)C NMR spectro...

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Detalles Bibliográficos
Autores principales: Osmanov, Vladimir K., Chipinsky, Evgeniy V., Khrustalev, Victor N., Novikov, Alexander S., Askerov, Rizvan Kamiloglu, Chizhov, Alexander O., Borisova, Galina N., Borisov, Alexander V., Grishina, Maria M., Kurasova, Margarita N., Kirichuk, Anatoly A., Peregudov, Alexander S., Kritchenkov, Andreii S., Tskhovrebov, Alexander G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504104/
https://www.ncbi.nlm.nih.gov/pubmed/36144534
http://dx.doi.org/10.3390/molecules27185799