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Bone-Marrow-Derived Mesenchymal Stem Cells, Their Conditioned Media, and Olive Leaf Extract Protect against Cisplatin-Induced Toxicity by Alleviating Oxidative Stress, Inflammation, and Apoptosis in Rats

Background: Hepatic and renal damage is a cisplatin (Cis)-induced deleterious effect that is a major limiting factor in clinical chemotherapy. Objectives: The current study was designed to investigate the influence of pretreatment with olive leaf extract (OLE), bone-marrow-derived mesenchymal stem c...

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Detalles Bibliográficos
Autores principales: Ibrahim, Mahrous A., Khalifa, Athar M., Mohamed, Alaa A., Galhom, Rania A., Korayem, Horeya E., Abd El-Fadeal, Noha M., Abd-Eltawab Tammam, Ahmed, Khalifa, Mohamed Mansour, Elserafy, Osama S., Abdel-Karim, Rehab I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504158/
https://www.ncbi.nlm.nih.gov/pubmed/36136492
http://dx.doi.org/10.3390/toxics10090526