SPIN90 Deficiency Ameliorates Amyloid β Accumulation by Regulating APP Trafficking in AD Model Mice

Alzheimer’s disease (AD), a common form of dementia, is caused in part by the aggregation and accumulation in the brain of amyloid β (Aβ), a product of the proteolytic cleavage of amyloid precursor protein (APP) in endosomes. Trafficking of APP, such as surface-intracellular recycling, is an early c...

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Detalles Bibliográficos
Autores principales: Oh, Youngsoo, Lee, Wongyoung, Kim, So Hee, Lee, Sooji, Kim, Byeong C., Lee, Kun Ho, Kim, Sung Hyun, Song, Woo Keun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504172/
https://www.ncbi.nlm.nih.gov/pubmed/36142484
http://dx.doi.org/10.3390/ijms231810563

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504172/
https://www.ncbi.nlm.nih.gov/pubmed/36142484
http://dx.doi.org/10.3390/ijms231810563

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