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SPIN90 Deficiency Ameliorates Amyloid β Accumulation by Regulating APP Trafficking in AD Model Mice

Alzheimer’s disease (AD), a common form of dementia, is caused in part by the aggregation and accumulation in the brain of amyloid β (Aβ), a product of the proteolytic cleavage of amyloid precursor protein (APP) in endosomes. Trafficking of APP, such as surface-intracellular recycling, is an early c...

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Detalles Bibliográficos
Autores principales:	Oh, Youngsoo, Lee, Wongyoung, Kim, So Hee, Lee, Sooji, Kim, Byeong C., Lee, Kun Ho, Kim, Sung Hyun, Song, Woo Keun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504172/ https://www.ncbi.nlm.nih.gov/pubmed/36142484 http://dx.doi.org/10.3390/ijms231810563

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