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Genetics, Functions, and Clinical Impact of Presenilin-1 (PSEN1) Gene
Presenilin-1 (PSEN1) has been verified as an important causative factor for early onset Alzheimer’s disease (EOAD). PSEN1 is a part of γ-secretase, and in addition to amyloid precursor protein (APP) cleavage, it can also affect other processes, such as Notch signaling, β-cadherin processing, and cal...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504248/ https://www.ncbi.nlm.nih.gov/pubmed/36142879 http://dx.doi.org/10.3390/ijms231810970 |