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Genetics, Functions, and Clinical Impact of Presenilin-1 (PSEN1) Gene

Presenilin-1 (PSEN1) has been verified as an important causative factor for early onset Alzheimer’s disease (EOAD). PSEN1 is a part of γ-secretase, and in addition to amyloid precursor protein (APP) cleavage, it can also affect other processes, such as Notch signaling, β-cadherin processing, and cal...

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Detalles Bibliográficos
Autores principales:	Bagaria, Jaya, Bagyinszky, Eva, An, Seong Soo A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504248/ https://www.ncbi.nlm.nih.gov/pubmed/36142879 http://dx.doi.org/10.3390/ijms231810970

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