Testing the Protective Effects of Sulfobutylether-Βeta-Cyclodextrin (SBECD) and Sugammadex against Chlorpromazine-Induced Acute Toxicity in SH-SY5Y Cell Line and in NMRI Mice

Chlorpromazine (CPZ) is an antipsychotic drug which can cause several adverse effects and drug poisoning. Recent studies demonstrated that CPZ forms highly stable complexes with certain cyclodextrins (CDs) such as sulfobutylether-β-CD (SBECD) and sugammadex (SGD). Since there is no available antidot...

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Detalles Bibliográficos
Autores principales: Fliszár-Nyúl, Eszter, Csepregi, Rita, Benkovics, Gábor, Szente, Lajos, Poór, Miklós
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504268/
https://www.ncbi.nlm.nih.gov/pubmed/36145637
http://dx.doi.org/10.3390/pharmaceutics14091888

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504268/
https://www.ncbi.nlm.nih.gov/pubmed/36145637
http://dx.doi.org/10.3390/pharmaceutics14091888

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