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Disruption of mitochondria-associated ER membranes impairs insulin sensitivity and thermogenic function of adipocytes

The prevalence and healthcare burden of obesity and its related metabolic disorders such as type 2 diabetes (T2D) are increasing rapidly. A better understanding of the pathogenesis of these diseases helps to find the therapeutic strategies. Mitochondria and endoplasmic reticulum (ER) are two importa...

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Detalles Bibliográficos
Autores principales: Wang, Chih-Hao, Wang, Chen-Hung, Hung, Pen-Jung, Wei, Yau-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504280/
https://www.ncbi.nlm.nih.gov/pubmed/36158195
http://dx.doi.org/10.3389/fcell.2022.965523