Tadalafil-Loaded Self-Nanoemulsifying Chewable Tablets for Improved Bioavailability: Design, In Vitro, and In Vivo Testing

This research aimed to develop innovative self-nanoemulsifying chewable tablets (SNECT) to increase oral bioavailability of tadalafil (TDL), a nearly insoluble phosphodiesterase-5 inhibitor. Cinnamon essential oil, PEG 40 hydrogenated castor oil (Cremophor(®) RH 40), and polyethylene glycol 400 serv...

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Detalles Bibliográficos
Autores principales: Ali, Hany S. M., Ahmed, Sameh A., Alqurshi, Abdulmalik A., Alalawi, Ali M., Shehata, Ahmed M., Alahmadi, Yaser M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504296/
https://www.ncbi.nlm.nih.gov/pubmed/36145675
http://dx.doi.org/10.3390/pharmaceutics14091927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504296/
https://www.ncbi.nlm.nih.gov/pubmed/36145675
http://dx.doi.org/10.3390/pharmaceutics14091927

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