Quantification of APOBEC3 Mutation Rates Affecting the VP1 Gene of BK Polyomavirus In Vivo

Mutations in the BK polyomavirus (BKPyV) capsid accumulate in kidney transplant (KTx) recipients with persistent virus replication. They are associated with neutralization escape and appear to arise as a result of cytosine deamination by host cell APOBEC3A/B enzymes. To study the mutagenic processes...

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Detalles Bibliográficos
Autores principales: McIlroy, Dorian, Peltier, Cécile, Nguyen, My-Linh, Manceau, Louise, Mobuchon, Lenha, Le Baut, Nicolas, Nguyen, Ngoc-Khanh, Tran, Minh-Chau, Nguyen, The-Cuong, Bressollette-Bodin, Céline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504301/
https://www.ncbi.nlm.nih.gov/pubmed/36146883
http://dx.doi.org/10.3390/v14092077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504301/
https://www.ncbi.nlm.nih.gov/pubmed/36146883
http://dx.doi.org/10.3390/v14092077

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