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Quantification of APOBEC3 Mutation Rates Affecting the VP1 Gene of BK Polyomavirus In Vivo
Mutations in the BK polyomavirus (BKPyV) capsid accumulate in kidney transplant (KTx) recipients with persistent virus replication. They are associated with neutralization escape and appear to arise as a result of cytosine deamination by host cell APOBEC3A/B enzymes. To study the mutagenic processes...
Autores principales: | McIlroy, Dorian, Peltier, Cécile, Nguyen, My-Linh, Manceau, Louise, Mobuchon, Lenha, Le Baut, Nicolas, Nguyen, Ngoc-Khanh, Tran, Minh-Chau, Nguyen, The-Cuong, Bressollette-Bodin, Céline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504301/ https://www.ncbi.nlm.nih.gov/pubmed/36146883 http://dx.doi.org/10.3390/v14092077 |
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