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Design, Rational Repurposing, Synthesis, In Vitro Evaluation, Homology Modeling and In Silico Study of Sulfuretin Analogs as Potential Antileishmanial Hit Compounds

Direct growth inhibition of infectious organisms coupled with immunomodulation to counteract the immunosuppressive environment might be a beneficial therapeutic approach. Herein, a library of sulfuretin analogs were developed with potential capabilities to inhibit production of the immunosuppressive...

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Detalles Bibliográficos
Autores principales: Hassan, Ahmed H.E., Phan, Trong-Nhat, Choi, Yeonwoo, Moon, Suyeon, No, Joo Hwan, Lee, Yong Sup
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504330/
https://www.ncbi.nlm.nih.gov/pubmed/36145279
http://dx.doi.org/10.3390/ph15091058