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Design, Rational Repurposing, Synthesis, In Vitro Evaluation, Homology Modeling and In Silico Study of Sulfuretin Analogs as Potential Antileishmanial Hit Compounds
Direct growth inhibition of infectious organisms coupled with immunomodulation to counteract the immunosuppressive environment might be a beneficial therapeutic approach. Herein, a library of sulfuretin analogs were developed with potential capabilities to inhibit production of the immunosuppressive...
Autores principales: | Hassan, Ahmed H.E., Phan, Trong-Nhat, Choi, Yeonwoo, Moon, Suyeon, No, Joo Hwan, Lee, Yong Sup |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504330/ https://www.ncbi.nlm.nih.gov/pubmed/36145279 http://dx.doi.org/10.3390/ph15091058 |
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