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Mechanistic Understanding of the Palmitoylation of G(o) Protein in the Allosteric Regulation of Adhesion Receptor GPR97

Adhesion G-protein-coupled receptors (aGPCRs)—a major family of GPCRs—play critical roles in the regulation of tissue development and cancer progression. The orphan receptor GPR97, activated by glucocorticoid stress hormones, is a prototypical aGPCR. Although it has been established that the palmito...

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Detalles Bibliográficos
Autores principales: Zhang, Hao, Chu, Guojun, Wang, Gaoming, Yao, Min, Lu, Shaoyong, Chen, Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504338/
https://www.ncbi.nlm.nih.gov/pubmed/36145604
http://dx.doi.org/10.3390/pharmaceutics14091856