Revisiting Cerebrospinal Fluid Flow Direction and Rate in Physiologically Based Pharmacokinetic Model

The bidirectional pulsatile movement of cerebrospinal fluid (CSF), instead of the traditionally believed unidirectional and constant CSF circulation, has been demonstrated. In the present study, the structure and parameters of the CSF compartments were revisited in our comprehensive and validated ce...

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Detalles Bibliográficos
Autores principales: Hirasawa, Makoto, de Lange, Elizabeth C. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504371/
https://www.ncbi.nlm.nih.gov/pubmed/36145511
http://dx.doi.org/10.3390/pharmaceutics14091764

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504371/
https://www.ncbi.nlm.nih.gov/pubmed/36145511
http://dx.doi.org/10.3390/pharmaceutics14091764

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