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Neuropeptide-Functionalized Gold Nanorod Enhanced Cellular Uptake and Improved In Vitro Photothermal Killing in LRP1-Positive Glioma Cells

The therapeutic modalities for glioblastoma multiforme fail badly due to the limitations of poor penetration through the blood–brain barrier and the lack of tumor targeting. In this study, we synthesized a neuropeptide (ANGIOPEP-2)-functionalized gold nanorod (GNR-ANGI-2) and systemically evaluated...

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Detalles Bibliográficos
Autores principales: Sankari, Sivasoorian Siva, Urade, Ritesh, Chiu, Chien-Chih, Wang, Li-Fang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504705/
https://www.ncbi.nlm.nih.gov/pubmed/36145687
http://dx.doi.org/10.3390/pharmaceutics14091939