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EPR Investigations to Study the Impact of Mito-Metformin on the Mitochondrial Function of Prostate Cancer Cells

Background: Mito-metformin10 (MM10), synthesized by attaching a triphenylphosphonium cationic moiety via a 10-carbon aliphatic side chain to metformin, is a mitochondria-targeted analog of metformin that was recently demonstrated to alter mitochondrial function and proliferation in pancreatic ductal...

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Detalles Bibliográficos
Autores principales: d’Hose, Donatienne, Mathieu, Barbara, Mignion, Lionel, Hardy, Micael, Ouari, Olivier, Jordan, Bénédicte F., Sonveaux, Pierre, Gallez, Bernard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504708/
https://www.ncbi.nlm.nih.gov/pubmed/36144606
http://dx.doi.org/10.3390/molecules27185872