Serum Collected from Preeclamptic Pregnancies Drives Vasoconstriction of Human Omental Arteries—A Novel Ex Vivo Model of Preeclampsia for Therapeutic Development

New-onset maternal hypertension is a hallmark of preeclampsia, driven by widespread endothelial dysfunction and systemic vasoconstriction. Here, we set out to create a new ex vivo model using preeclamptic serum to cause injury to the endothelium, mimicking vascular dysfunction in preeclampsia and of...

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Detalles Bibliográficos
Autores principales: Fato, Bianca R., de Alwis, Natasha, Beard, Sally, Binder, Natalie K., Pritchard, Natasha, Tong, Stephen, Kaitu’u-Lino, Tu’uhevaha J., Hannan, Natalie J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504727/
https://www.ncbi.nlm.nih.gov/pubmed/36142764
http://dx.doi.org/10.3390/ijms231810852

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504727/
https://www.ncbi.nlm.nih.gov/pubmed/36142764
http://dx.doi.org/10.3390/ijms231810852

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