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Atomic Simulation of the Binding of JAK1 and JAK2 with the Selective Inhibitor Ruxolitinib

Rheumatoid arthritis belongs to the group of chronic systemic autoimmune diseases characterized by the development of destructive synovitis and extra-articular manifestations. Cytokines regulate a wide range of inflammatory processes involved in the pathogenesis of rheumatoid arthritis and contribut...

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Detalles Bibliográficos
Autores principales: Kondratyev, Maxim, Rudnev, Vladimir R., Nikolsky, Kirill S., Stepanov, Alexander A., Petrovsky, Denis V., Kulikova, Liudmila I., Kopylov, Arthur T., Malsagova, Kristina A., Kaysheva, Anna L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504736/
https://www.ncbi.nlm.nih.gov/pubmed/36142375
http://dx.doi.org/10.3390/ijms231810466