Dosimetry of [(212)Pb]VMT01, a MC1R-Targeted Alpha Therapeutic Compound, and Effect of Free (208)Tl on Tissue Absorbed Doses

[(212)Pb]VMT01 is a melanocortin 1 receptor (MC1R) targeted theranostic ligand in clinical development for alpha particle therapy for melanoma. (212)Pb has an elementally matched gamma-emitting isotope (203)Pb; thus, [(203)Pb]VMT01 can be used as an imaging surrogate for [(212)Pb]VMT01. [(212)Pb]VMT...

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Detalles Bibliográficos
Autores principales: Orcutt, Kelly D., Henry, Kelly E., Habjan, Christine, Palmer, Keryn, Heimann, Jack, Cupido, Julie M., Gottumukkala, Vijay, Cissell, Derek D., Lyon, Morgan C., Hussein, Amira I., Liu, Dijie, Li, Mengshi, Johnson, Frances L., Schultz, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504749/
https://www.ncbi.nlm.nih.gov/pubmed/36144563
http://dx.doi.org/10.3390/molecules27185831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504749/
https://www.ncbi.nlm.nih.gov/pubmed/36144563
http://dx.doi.org/10.3390/molecules27185831

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