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Dosimetry of [(212)Pb]VMT01, a MC1R-Targeted Alpha Therapeutic Compound, and Effect of Free (208)Tl on Tissue Absorbed Doses
[(212)Pb]VMT01 is a melanocortin 1 receptor (MC1R) targeted theranostic ligand in clinical development for alpha particle therapy for melanoma. (212)Pb has an elementally matched gamma-emitting isotope (203)Pb; thus, [(203)Pb]VMT01 can be used as an imaging surrogate for [(212)Pb]VMT01. [(212)Pb]VMT...
Autores principales: | Orcutt, Kelly D., Henry, Kelly E., Habjan, Christine, Palmer, Keryn, Heimann, Jack, Cupido, Julie M., Gottumukkala, Vijay, Cissell, Derek D., Lyon, Morgan C., Hussein, Amira I., Liu, Dijie, Li, Mengshi, Johnson, Frances L., Schultz, Michael K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504749/ https://www.ncbi.nlm.nih.gov/pubmed/36144563 http://dx.doi.org/10.3390/molecules27185831 |
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