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Exposure–Response Analysis of Osimertinib in Patients with Advanced Non-Small-Cell Lung Cancer

High interindividual variability (IIV) of the clinical response to epidermal growth factor receptor (EGFR) inhibitors such as osimertinib in non-small-cell lung cancer (NSCLC) might be related to the IIV in plasma exposure. The aim of this study was to evaluate the exposure–response relationship for...

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Detalles Bibliográficos
Autores principales: Rodier, Thomas, Puszkiel, Alicja, Cardoso, Evelina, Balakirouchenane, David, Narjoz, Céline, Arrondeau, Jennifer, Fallet, Vincent, Khoudour, Nihel, Guidi, Monia, Vidal, Michel, Declèves, Xavier, Csajka, Chantal, Alexandre, Jérôme, Cadranel, Jacques, Fabre, Elizabeth, Wislez, Marie, Goldwasser, François, Blanchet, Benoit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504753/
https://www.ncbi.nlm.nih.gov/pubmed/36145591
http://dx.doi.org/10.3390/pharmaceutics14091844