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Exposure–Response Analysis of Osimertinib in Patients with Advanced Non-Small-Cell Lung Cancer
High interindividual variability (IIV) of the clinical response to epidermal growth factor receptor (EGFR) inhibitors such as osimertinib in non-small-cell lung cancer (NSCLC) might be related to the IIV in plasma exposure. The aim of this study was to evaluate the exposure–response relationship for...
Autores principales: | Rodier, Thomas, Puszkiel, Alicja, Cardoso, Evelina, Balakirouchenane, David, Narjoz, Céline, Arrondeau, Jennifer, Fallet, Vincent, Khoudour, Nihel, Guidi, Monia, Vidal, Michel, Declèves, Xavier, Csajka, Chantal, Alexandre, Jérôme, Cadranel, Jacques, Fabre, Elizabeth, Wislez, Marie, Goldwasser, François, Blanchet, Benoit |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504753/ https://www.ncbi.nlm.nih.gov/pubmed/36145591 http://dx.doi.org/10.3390/pharmaceutics14091844 |
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