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AP39, a Mitochondrial-Targeted H(2)S Donor, Improves Porcine Islet Survival in Culture

The rapid deterioration of transplanted islets in culture is a well-established phenomenon. We recently reported that pancreas preservation with AP39 reduces reactive oxygen species (ROS) production and improves islet graft function. In this study, we investigated whether the addition of AP39 to the...

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Detalles Bibliográficos
Autores principales: Shinzato, Misaki, Miyagi-Shiohira, Chika, Kuwae, Kazuho, Nishime, Kai, Tamaki, Yoshihito, Yonaha, Tasuku, Sakai-Yonaha, Mayuko, Yamasaki, Ikuo, Otsuka, Ryusei, Saitoh, Issei, Watanabe, Masami, Noguchi, Hirofumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504761/
https://www.ncbi.nlm.nih.gov/pubmed/36143032
http://dx.doi.org/10.3390/jcm11185385