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Arabinoxylans-Based Oral Insulin Delivery System Targeting the Colon: Simulation in a Human Intestinal Microbial Ecosystem and Evaluation in Diabetic Rats

Arabinoxylans (AX) microcapsules loaded with insulin were prepared by enzymatic gelation of AX, using a triaxial electrospray method. The microcapsules presented a spherical shape, with an average size of 250 µm. The behavior of AX microcapsules was evaluated using a simulator of the human intestina...

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Detalles Bibliográficos
Autores principales: Martínez-López, Ana L., Carvajal-Millan, Elizabeth, Canett-Romero, Rafael, Prakash, Satya, Rascón-Chu, Agustín, López-Franco, Yolanda L., Lizardi-Mendoza, Jaime, Micard, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504777/
https://www.ncbi.nlm.nih.gov/pubmed/36145283
http://dx.doi.org/10.3390/ph15091062