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Defining Specific Cell States of MPTP-Induced Parkinson’s Disease by Single-Nucleus RNA Sequencing

Parkinson’s disease (PD) is a neurodegenerative disease with an impairment of movement execution that is related to age and genetic and environmental factors. 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) is a neurotoxin widely used to induce PD models, but the effect of MPTP on the cells and...

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Detalles Bibliográficos
Autores principales: Guo, Yunxia, Ma, Junjie, Huang, Hao, Xu, Jitao, Jiang, Chao, Ye, Kaiqiang, Chang, Ning, Ge, Qinyu, Wang, Guangzhong, Zhao, Xiangwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504791/
https://www.ncbi.nlm.nih.gov/pubmed/36142685
http://dx.doi.org/10.3390/ijms231810774