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Asynchronous excitatory neuron development in an isogenic cortical spheroid model of Down syndrome

The intellectual disability (ID) in Down syndrome (DS) is thought to result from a variety of developmental deficits such as alterations in neural progenitor division, neurogenesis, gliogenesis, cortical architecture, and reduced cortical volume. However, the molecular processes underlying these neu...

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Detalles Bibliográficos
Autores principales: Li, Zhen, Klein, Jenny A., Rampam, Sanjeev, Kurzion, Ronni, Campbell, Natalie Baker, Patel, Yesha, Haydar, Tarik F., Zeldich, Ella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504873/
https://www.ncbi.nlm.nih.gov/pubmed/36161168
http://dx.doi.org/10.3389/fnins.2022.932384