Use of Real‐World Data and Physiologically‐Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity

Dosing guidance for children with obesity is often unknown despite the fact that nearly 20% of US children are classified as obese. Enoxaparin, a commonly prescribed low‐molecular‐weight heparin, is dosed based on body weight irrespective of obesity status to achieve maximum concentration within a n...

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Detalles Bibliográficos
Autores principales: Gerhart, Jacqueline G., Carreño, Fernando O., Loop, Matthew Shane, Lee, Craig R., Edginton, Andrea N., Sinha, Jaydeep, Kumar, Karan R., Kirkpatrick, Carl M., Hornik, Christoph P., Gonzalez, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504927/
https://www.ncbi.nlm.nih.gov/pubmed/35451072
http://dx.doi.org/10.1002/cpt.2618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504927/
https://www.ncbi.nlm.nih.gov/pubmed/35451072
http://dx.doi.org/10.1002/cpt.2618

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