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Use of Real‐World Data and Physiologically‐Based Pharmacokinetic Modeling to Characterize Enoxaparin Disposition in Children With Obesity
Dosing guidance for children with obesity is often unknown despite the fact that nearly 20% of US children are classified as obese. Enoxaparin, a commonly prescribed low‐molecular‐weight heparin, is dosed based on body weight irrespective of obesity status to achieve maximum concentration within a n...
Autores principales: | Gerhart, Jacqueline G., Carreño, Fernando O., Loop, Matthew Shane, Lee, Craig R., Edginton, Andrea N., Sinha, Jaydeep, Kumar, Karan R., Kirkpatrick, Carl M., Hornik, Christoph P., Gonzalez, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504927/ https://www.ncbi.nlm.nih.gov/pubmed/35451072 http://dx.doi.org/10.1002/cpt.2618 |
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