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Thymoquinone Inhibits JAK/STAT and PI3K/Akt/ mTOR Signaling Pathways in MV4-11 and K562 Myeloid Leukemia Cells

Constitutive activation of Janus tyrosine kinase-signal transducer and activator of transcription (JAK/STAT) and Phosphatidylinositol 3-kinase/Akt/mammalian target of rapamycin (PI3K/Akt/mTOR) signaling pathways plays a crucial role in the development of acute myeloid leukemia (AML) and chronic myel...

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Detalles Bibliográficos
Autores principales: Al-Rawashde, Futoon Abedrabbu, Al-wajeeh, Abdullah Saleh, Vishkaei, Mansoureh Nazari, Saad, Hanan Kamel M., Johan, Muhammad Farid, Taib, Wan Rohani Wan, Ismail, Imilia, Al-Jamal, Hamid Ali Nagi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504933/
https://www.ncbi.nlm.nih.gov/pubmed/36145344
http://dx.doi.org/10.3390/ph15091123