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Comprehensive Analysis of Adverse Events Induced by PARP Inhibitors Using JADER and Time to Onset

Poly (ADP-ribose) polymerase (PARP) inhibitors are effective against breast cancer susceptibility gene (BRCA) mutations. Clinical trials have reported hematologic toxicity and gastrointestinal symptoms as class effects of PARP inhibitors. However, information on adverse events (AEs) in a Japanese cl...

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Detalles Bibliográficos
Autores principales: Yamaoka, Kenta, Fujiwara, Masaki, Uchida, Mayako, Uesawa, Yoshihiro, Muroi, Nobuyuki, Shimizu, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9504973/
https://www.ncbi.nlm.nih.gov/pubmed/36143391
http://dx.doi.org/10.3390/life12091355