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Orally Administered Amphotericin B Nanoformulations: Physical Properties of Nanoparticle Carriers on Bioavailability and Clinical Relevance

Amphotericin B is an effective polyene antifungal considered as a “gold standard” in the management of fungal infections. Currently, it is administered mainly by IV due to poor aqueous solubility, which precludes its delivery orally. Paradoxically, IV administration is akin to side effects that have...

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Detalles Bibliográficos
Autores principales: Fairuz, Shadreen, Nair, Rajesh Sreedharan, Billa, Nashiru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505005/
https://www.ncbi.nlm.nih.gov/pubmed/36145572
http://dx.doi.org/10.3390/pharmaceutics14091823