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Extraction, purification, structure, modification, and biological activity of traditional Chinese medicine polysaccharides: A review

Traditional Chinese medicines (TCM), as the unique natural resource, are rich in polysaccharides, polyphenols, proteins, amino acid, fats, vitamins, and other components. Hence, TCM have high medical and nutritional values. Polysaccharides are one of the most important active components in TCM. Grow...

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Autores principales: Xue, Hongkun, Li, Pengcheng, Bian, Jiayue, Gao, Yuchao, Sang, Yumei, Tan, Jiaqi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505017/
https://www.ncbi.nlm.nih.gov/pubmed/36159471
http://dx.doi.org/10.3389/fnut.2022.1005181
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author Xue, Hongkun
Li, Pengcheng
Bian, Jiayue
Gao, Yuchao
Sang, Yumei
Tan, Jiaqi
author_facet Xue, Hongkun
Li, Pengcheng
Bian, Jiayue
Gao, Yuchao
Sang, Yumei
Tan, Jiaqi
author_sort Xue, Hongkun
collection PubMed
description Traditional Chinese medicines (TCM), as the unique natural resource, are rich in polysaccharides, polyphenols, proteins, amino acid, fats, vitamins, and other components. Hence, TCM have high medical and nutritional values. Polysaccharides are one of the most important active components in TCM. Growing reports have indicated that TCM polysaccharides (TCMPs) have various biological activities, such as antioxidant, anti-aging, immunomodulatory, hypoglycemic, hypolipidemic, anti-tumor, anti-inflammatory, and other activities. Hence, the research progresses and future prospects of TCMPs must be systematically reviewed to promote their better understanding. The aim of this review is to provide comprehensive and systematic recombinant information on the extraction, purification, structure, chemical modification, biological activities, and potential mechanism of TCMPs to support their therapeutic effects and health functions. The findings provide new valuable insights and theoretical basis for future research and development of TCMPs.
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spelling pubmed-95050172022-09-24 Extraction, purification, structure, modification, and biological activity of traditional Chinese medicine polysaccharides: A review Xue, Hongkun Li, Pengcheng Bian, Jiayue Gao, Yuchao Sang, Yumei Tan, Jiaqi Front Nutr Nutrition Traditional Chinese medicines (TCM), as the unique natural resource, are rich in polysaccharides, polyphenols, proteins, amino acid, fats, vitamins, and other components. Hence, TCM have high medical and nutritional values. Polysaccharides are one of the most important active components in TCM. Growing reports have indicated that TCM polysaccharides (TCMPs) have various biological activities, such as antioxidant, anti-aging, immunomodulatory, hypoglycemic, hypolipidemic, anti-tumor, anti-inflammatory, and other activities. Hence, the research progresses and future prospects of TCMPs must be systematically reviewed to promote their better understanding. The aim of this review is to provide comprehensive and systematic recombinant information on the extraction, purification, structure, chemical modification, biological activities, and potential mechanism of TCMPs to support their therapeutic effects and health functions. The findings provide new valuable insights and theoretical basis for future research and development of TCMPs. Frontiers Media S.A. 2022-09-09 /pmc/articles/PMC9505017/ /pubmed/36159471 http://dx.doi.org/10.3389/fnut.2022.1005181 Text en Copyright © 2022 Xue, Li, Bian, Gao, Sang and Tan. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Nutrition
Xue, Hongkun
Li, Pengcheng
Bian, Jiayue
Gao, Yuchao
Sang, Yumei
Tan, Jiaqi
Extraction, purification, structure, modification, and biological activity of traditional Chinese medicine polysaccharides: A review
title Extraction, purification, structure, modification, and biological activity of traditional Chinese medicine polysaccharides: A review
title_full Extraction, purification, structure, modification, and biological activity of traditional Chinese medicine polysaccharides: A review
title_fullStr Extraction, purification, structure, modification, and biological activity of traditional Chinese medicine polysaccharides: A review
title_full_unstemmed Extraction, purification, structure, modification, and biological activity of traditional Chinese medicine polysaccharides: A review
title_short Extraction, purification, structure, modification, and biological activity of traditional Chinese medicine polysaccharides: A review
title_sort extraction, purification, structure, modification, and biological activity of traditional chinese medicine polysaccharides: a review
topic Nutrition
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505017/
https://www.ncbi.nlm.nih.gov/pubmed/36159471
http://dx.doi.org/10.3389/fnut.2022.1005181
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