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Synthesis of Hydantoin Androgen Receptor Antagonists and Study on Their Antagonistic Activity

Hydroxymethylthiohydantoin, hydroxymethylthiohydantoin, and hydantoin, containing a pyridine group, were synthesized to study their androgen receptor antagonistic activities. Among them, compounds 6a/6c/7g/19a/19b exhibited excellent androgen receptor antagonistic activity, which was consistent with...

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Detalles Bibliográficos
Autores principales:	Ma, Longjun, Zhou, Yan, Yang, Dehua, Wang, Ming-Wei, Lu, Wei, Jin, Jiyu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505067/ https://www.ncbi.nlm.nih.gov/pubmed/36144603 http://dx.doi.org/10.3390/molecules27185867

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