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Immunogenicity and Protective Efficacy of a Recombinant Pichinde Viral-Vectored Vaccine Expressing Influenza Virus Hemagglutinin Antigen in Pigs

Influenza A virus of swine (IAV-S) is an economically important swine pathogen. The IAV-S hemagglutinin (HA) surface protein is the main target for vaccine development. In this study, we evaluated the feasibility of using the recombinant tri-segmented Pichinde virus (rPICV) as a viral vector to deli...

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Detalles Bibliográficos
Autores principales: Kumari, Sushmita, Chaudhari, Jayeshbhai, Huang, Qinfeng, Gauger, Phillip, De Almeida, Marcelo Nunes, Liang, Yuying, Ly, Hinh, Vu, Hiep L. X.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505097/
https://www.ncbi.nlm.nih.gov/pubmed/36146478
http://dx.doi.org/10.3390/vaccines10091400