UPLC-LTQ-Orbitrap-Based Cell Metabolomics and Network Pharmacology Analysis to Reveal the Potential Antiarthritic Effects of Pristimerin: In Vitro, In Silico and In Vivo Study

Rheumatoid arthritis (RA) is characterized by systemic inflammation and synovial hyperplasia. Pristimerin, a natural triterpenoid isolated from plants belonging to the Celastraceae and Hippocrateaceae families, has been reported to exhibit anti-inflammation and anti-proliferation activities. Our stu...

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Detalles Bibliográficos
Autores principales: Lv, Mengying, Liang, Qiaoling, Luo, Zhaoyong, Han, Bo, Ni, Tengyang, Wang, Yang, Tao, Li, Lyu, Weiting, Xiang, Jie, Liu, Yanqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505172/
https://www.ncbi.nlm.nih.gov/pubmed/36144243
http://dx.doi.org/10.3390/metabo12090839

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505172/
https://www.ncbi.nlm.nih.gov/pubmed/36144243
http://dx.doi.org/10.3390/metabo12090839

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