Generation and Characterization of Drug-Resistant Influenza B Viruses Selected In Vitro with Baloxavir Acid

Baloxavir marboxil (BXM) is an antiviral drug that targets the endonuclease of the influenza polymerase acidic (PA) protein. Antiviral resistance, mainly mediated by the I38T PA substitution, readily occurs in both A(H1N1) and A(H3N2) viruses following a single dose of BXM. Influenza B resistance to...

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Detalles Bibliográficos
Autores principales: Saim-Mamoun, Amel, Abed, Yacine, Carbonneau, Julie, Boivin, Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505253/
https://www.ncbi.nlm.nih.gov/pubmed/36145480
http://dx.doi.org/10.3390/pathogens11091048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505253/
https://www.ncbi.nlm.nih.gov/pubmed/36145480
http://dx.doi.org/10.3390/pathogens11091048

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