Coordination Sites for Sodium and Potassium Ions in Nucleophilic Adeninate Contact ion-Pairs: A Molecular-Wide and Electron Density-Based (MOWED) Perspective

The adeninate anion (Ade(−)) is a useful nucleophile used in the synthesis of many prodrugs (including those for HIV AIDS treatment). It exists as a contact ion-pair (CIP) with Na(+) and K(+) (M(+)) but the site of coordination is not obvious from spectroscopic data. Herein, a molecular-wide and ele...

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Detalles Bibliográficos
Autores principales: Buyens, Dominique M. S., Pilcher, Lynne A., Cukrowski, Ignacy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505275/
https://www.ncbi.nlm.nih.gov/pubmed/36144844
http://dx.doi.org/10.3390/molecules27186111

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505275/
https://www.ncbi.nlm.nih.gov/pubmed/36144844
http://dx.doi.org/10.3390/molecules27186111

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