Discovery of Potential SARS-CoV-2 Papain-like Protease Natural Inhibitors Employing a Multi-Phase In Silico Approach

As an extension of our research against COVID-19, a multiphase in silico approach was applied in the selection of the three most common inhibitors (Glycyrrhizoflavone (76), Arctigenin (94), and Thiangazole (298)) against papain-like protease, PLpro (PDB ID: 4OW0), among 310 metabolites of natural or...

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Detalles Bibliográficos
Autores principales: Elkaeed, Eslam B., Metwaly, Ahmed M., Alesawy, Mohamed S., Saleh, Abdulrahman M., Alsfouk, Aisha A., Eissa, Ibrahim H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505301/
https://www.ncbi.nlm.nih.gov/pubmed/36143445
http://dx.doi.org/10.3390/life12091407

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505301/
https://www.ncbi.nlm.nih.gov/pubmed/36143445
http://dx.doi.org/10.3390/life12091407

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