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Healthy-like CD4(+) Regulatory and CD4(+) Conventional T-Cell Receptor Repertoires Predict Protection from GVHD Following Donor Lymphocyte Infusion
Donor lymphocyte infusion (DLI) can (re-)induce durable remission in relapsing patients after allogeneic hematopoietic stem-cell transplantation (alloHSCT). However, DLI harbors the risk of increased non-relapse mortality due to the co-occurrence of graft-versus-host disease (GVHD). GVHD onset may b...
Autores principales: | Schneider, Jessica, Kuhlmann, Leonie, Xiao, Yankai, Raha, Solaiman, Bernhardt, Günter, Stadler, Michael, Thol, Felicitas, Heuser, Michael, Eder, Matthias, Ganser, Arnold, Ravens, Sarina, Förster, Reinhold, Prinz, Immo, Koenecke, Christian, Schultze-Florey, Christian R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505302/ https://www.ncbi.nlm.nih.gov/pubmed/36142824 http://dx.doi.org/10.3390/ijms231810914 |
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