Activation of Alternative Bilirubin Clearance Pathways Partially Reduces Hyperbilirubinemia in a Mouse Model Lacking Functional Ugt1a1 Activity

Bilirubin is a heme catabolite and Ugt1a1 is the only enzyme involved in the biological elimination of bilirubin. Partially functional or non-functional Ugt1a1 may result in neuronal damage and death due to the accumulation of unconjugated bilirubin in the brain. The understanding of the role of alt...

Descripción completa

Detalles Bibliográficos
Autores principales: Banerjee, Bhaswati, Olajide, Olayemi Joseph, Bortolussi, Giulia, Muro, Andrés F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505366/
https://www.ncbi.nlm.nih.gov/pubmed/36142606
http://dx.doi.org/10.3390/ijms231810703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505366/
https://www.ncbi.nlm.nih.gov/pubmed/36142606
http://dx.doi.org/10.3390/ijms231810703

Ejemplares similares