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Targeting of the Mitochondrial TET1 Protein by Pyrrolo[3,2-b]pyrrole Chelators

Targeting of epigenetic mechanisms, such as the hydroxymethylation of DNA, has been intensively studied, with respect to the treatment of many serious pathologies, including oncological disorders. Recent studies demonstrated that promising therapeutic strategies could potentially be based on the inh...

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Detalles Bibliográficos
Autores principales: Antonyová, Veronika, Tatar, Ameneh, Brogyányi, Tereza, Kejík, Zdeněk, Kaplánek, Robert, Vellieux, Fréderic, Abramenko, Nikita, Sinica, Alla, Hajduch, Jan, Novotný, Petr, Masters, Bettie Sue, Martásek, Pavel, Jakubek, Milan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505425/
https://www.ncbi.nlm.nih.gov/pubmed/36142763
http://dx.doi.org/10.3390/ijms231810850