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Effective Preparation of [(18)F]Flumazenil Using Copper-Mediated Late-Stage Radiofluorination of a Stannyl Precursor
(1) Background: [(18)F]Flumazenil 1 ([(18)F]FMZ) is an established positron emission tomography (PET) radiotracer for the imaging of the gamma-aminobutyric acid (GABA) receptor subtype, GABA(A) in the brain. The production of [(18)F]FMZ 1 for its clinical use has proven to be challenging, requiring...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505495/ https://www.ncbi.nlm.nih.gov/pubmed/36144667 http://dx.doi.org/10.3390/molecules27185931 |