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Evaluation of Plant Ceramide Species-Induced Exosome Release from Neuronal Cells and Exosome Loading Using Deuterium Chemistry

The extracellular accumulation of aggregated amyloid-β (Aβ) in the brain leads to the early pathology of Alzheimer’s disease (AD). The administration of exogenous plant-type ceramides into AD model mice can promote the release of neuronal exosomes, a subtype of extracellular vesicles, that can media...

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Detalles Bibliográficos
Autores principales: Murai, Yuta, Honda, Takumi, Yuyama, Kohei, Mikami, Daisuke, Eguchi, Koichi, Ukawa, Yuichi, Usuki, Seigo, Igarashi, Yasuyuki, Monde, Kenji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505575/
https://www.ncbi.nlm.nih.gov/pubmed/36142663
http://dx.doi.org/10.3390/ijms231810751