Simultaneous Imaging and Therapy Using Epitope-Specific Anti-Epidermal Growth Factor Receptor (EGFR) Antibody Conjugates

Matuzumab and nimotuzumab are anti-EGFR monoclonal antibodies that bind to different epitopes of domain III of EGFR. We developed (89)Zr-matuzumab as a PET probe for diagnosis/monitoring of response to treatment of a noncompeting anti-EGFR nimotuzumab antibody drug conjugate (ADC) using mouse colore...

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Detalles Bibliográficos
Autores principales: Tikum, Anjong Florence, Nambisan, Anand Krishnan, Ketchemen, Jessica Pougoue, Babeker, Hanan, Khan, Musharraf N., Torlakovic, Emina E., Fonge, Humphrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505583/
https://www.ncbi.nlm.nih.gov/pubmed/36145664
http://dx.doi.org/10.3390/pharmaceutics14091917

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505583/
https://www.ncbi.nlm.nih.gov/pubmed/36145664
http://dx.doi.org/10.3390/pharmaceutics14091917

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