Fluorine Atoms on C(6)H(5)-Corrole Affect the Interaction with M(pro) and PL(pro) Proteases of SARS-CoV-2: Molecular Docking and 2D-QSAR Approaches

The chymotrypsin-like cysteine protease (3CL(pro), also known as main protease—M(pro)) and papain-like protease (PL(pro)) of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have been used as the main targets for screening potential synthetic inhibitors for posterior in vitro evaluation...

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Detalles Bibliográficos
Autores principales: Chaves, Otávio Augusto, Rodrigues-Santos, Cláudio Eduardo, Echevarria, Áurea, Sacramento, Carolina Q., Fintelman-Rodrigues, Natalia, Temerozo, Jairo R., Castro-Faria-Neto, Hugo Caire, Souza, Thiago Moreno Lopes e
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505658/
https://www.ncbi.nlm.nih.gov/pubmed/36142848
http://dx.doi.org/10.3390/ijms231810936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505658/
https://www.ncbi.nlm.nih.gov/pubmed/36142848
http://dx.doi.org/10.3390/ijms231810936

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