Explaining the Release Mechanism of Ritonavir/PVPVA Amorphous Solid Dispersions

In amorphous solid dispersions (ASDs), an active pharmaceutical ingredient (API) is dissolved on a molecular level in a polymeric matrix. The API is expected to be released from the ASD upon dissolution in aqueous media. However, a series of earlier works observed a drastic collapse of the API relea...

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Detalles Bibliográficos
Autores principales: Krummnow, Adrian, Danzer, Andreas, Voges, Kristin, Dohrn, Stefanie, Kyeremateng, Samuel O., Degenhardt, Matthias, Sadowski, Gabriele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505701/
https://www.ncbi.nlm.nih.gov/pubmed/36145652
http://dx.doi.org/10.3390/pharmaceutics14091904

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9505701/
https://www.ncbi.nlm.nih.gov/pubmed/36145652
http://dx.doi.org/10.3390/pharmaceutics14091904

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